Application of recombinant antigens to blood group diagnostics
نویسندگان
چکیده
منابع مشابه
Relationship of blood groups to pemphigus: Do blood group antigens have a biological role? A Case-control study
Background: ABO blood group antigens may play a role in the pathophysiology of certain diseases. Several studies have investigated the relation between blood group and autoimmune disorders. In this research, we evaluated the associations between ABO blood types and rhesus (Rh) factor in pemphigus patients.Methods: In this case-control, hospital-based study, we evaluated the prevalence of blood ...
متن کاملBiological roles of blood group antigens.
Recognition and application of blood group differences on human red cells permitted the development of safe procedures for blood transfusion. Blood group antigens are markers on surface-exposed red cell proteins or the sugar moiety of glycoproteins or glycolipids. Apart from their presumed biological function, some antigens have been identified as receptors for host/parasite interactions. Thus,...
متن کاملPassive modulation of blood-group antigens.
Rh-positive erythrocytes were enriched and depleted of membrane cholesterol, and the mediated change in the degree of exposure of the D antigens was determined by fluorescence-activated cell sorting, using indirect fluorescent antibody labeling. The results are compatible with a model in which the expression of the D antigens can be modulated significantly by the lipid microviscosity (eta). At ...
متن کاملNorovirus Binding to Ligands Beyond Histo-Blood Group Antigens
Histo-blood group antigens (HBGAs) are commonly accepted as the cellular receptors for human norovirus. However, some human noroviruses have been found not to bind any HBGA ligand, suggesting potential additional co-factors. Some ligands have been found to bind noroviruses and have the potential to be additional cellular receptors/attachment factors for human norovirus or inhibitors of the HBGA...
متن کاملABO blood-group antigens in oral cancer.
Tumor progression is often associated with altered glycosylation of the cell-surface proteins and lipids. The peripheral part of these cell-surface glycoconjugates often carries carbohydrate structures related to the ABO and Lewis blood-group antigens. The expression of histo-blood-group antigens in normal human tissues is dependent on the type of differentiation of the epithelium. In most huma...
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ژورنال
عنوان ژورنال: ISBT Science Series
سال: 2011
ISSN: 1751-2816
DOI: 10.1111/j.1751-2824.2011.01428.x